Nandini... What is your senior project?

What a great question! I'd like you all to reach way back in time... not too far... just to March. Remember my first post? It kind of explained what I was doing, but "kind of" doesn't cut it. Hopefully these next few paragraphs will give you all a fuller, better, and deeper understanding.

In my last post, I mentioned that the cellular response to the different radiation methods have yet to be investigated.

The University of Arizona Center for Applied Nanobioscience and Medicine has come of with a preliminary study to evaluate these responses.

The question: Is there a difference in cellular response between high single (1x10Gy) and fractionated dose (5x2Gy) radiation therapy?

The high single dose is used to model the hypofractionated regimen and the fractionated dose is used to model the conventional regimen. 

For this study we utilized the three prostate cancer cell lines: 22Rv1, DU145, and PC3. We conducted a gene analysis, clonogenic assay, and proliferation assay. 

The gene a analysis was the CLPA Assay and CE Analysis. 

The clonogenic assay was used to evaluate radioresistance and the proliferation assay was used to evaluate multiplication.